SNAP-8 is a synthetic octapeptide, meaning it is composed of a chain of eight amino acids, and it is an extended analog of the well-known peptide Argireline (Acetyl Hexapeptide-3). It belongs to a class of peptides sometimes referred to as neurotransmitter-inhibiting peptides, and it is designed to mimic a segment of the SNAP-25 protein, which plays a role in the release of neurotransmitters at neuromuscular junctions. SNAP-8 is a fully synthetic compound and is not derived from a natural biological source, though its sequence is based on naturally occurring protein structures. In laboratory and cosmetic research settings, it has been studied for its potential to modulate the signaling processes involved in muscle contraction at the cellular level. All research involving SNAP-8 is conducted strictly for scientific and investigational purposes, and it is not intended for human use or consumption.
| CAS Number | 868844-74-0 |
| Molecular Formula | C42H72N16O15S |
| Molecular Weight | 1,073.20 g/mol |
| IUPAC Name | (4S)-4-acetamido-5-[[(2S)-1-[[(2S)-1-[[(2S)-5-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-3-carboxy-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-1,5-dioxopentan-2-yl]amino]-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-carboxy-1-oxobutan-2-yl]amino]hex-5-enoic acid |
| PubChem CID | 71587832 |
SNAP-8 is a synthetic octapeptide that researchers have studied primarily in the context of neuromuscular signaling, specifically in relation to the mechanisms that govern muscle contraction at the dermal level. Studies have examined its potential interactions with components of the SNARE protein complex — a molecular system involved in the release of neurotransmitters at neuromuscular junctions — with particular interest in how interfering with this pathway might influence voluntary facial muscle activity in laboratory models. Research has investigated this peptide using in vitro cell-based assays and cosmetic efficacy models, making it a subject of interest in the field of topical and dermatological research rather than systemic pharmacology. Published research on SNAP-8 specifically is limited, and much of what is understood about its biochemical behavior is inferred from studies on related peptides and the broader SNARE signaling literature. As with all research peptides, findings from laboratory and preclinical settings are intended solely to advance scientific understanding and do not constitute a basis for human therapeutic use.
No published research abstracts are currently available for this compound in our database.