Vialox, also known by its INCI name Pentapeptide-3 and assigned CAS number 135679-88-8, is a synthetic pentapeptide composed of five amino acids — glycine, proline, arginine, proline, and alanine — arranged in a specific sequence that has drawn attention in cosmetic and biochemical research. It is classified as a neurotransmitter-inhibiting peptide, designed to mimic the mechanism of certain compounds that modulate acetylcholine receptor activity at the neuromuscular junction, a process that has made it of interest in skin biology research. Vialox is sometimes grouped alongside other cosmeceutical peptides studied for their potential interactions with the extracellular matrix and skin aging processes, including effects on collagen and elastin structure. Published research has begun exploring its antiaging properties through both computational modeling and laboratory-based methods, with early studies comparing its activity to related peptides such as Leuphasyl. As with all compounds featured on this site, Vialox is intended strictly for research and scientific study purposes and is not approved for human use or consumption.
| CAS Number | 135679-88-8 |
| Molecular Formula | C21H37N9O5 |
| Molecular Weight | 495.60 g/mol |
| IUPAC Name | (2S)-1-(2-aminoacetyl)-N-[(2S)-1-[(2S)-2-[[(2S)-1-amino-1-oxopropan-2-yl]carbamoyl]pyrrolidin-1-yl]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]pyrrolidine-2-carboxamide |
| PubChem CID | 11605666 |
Vialox is a synthetic pentapeptide that researchers have studied primarily in the context of skin biology, with particular attention to its potential role in processes related to extracellular matrix maintenance and the molecular mechanisms underlying skin aging. Studies have examined how this peptide interacts with components involved in the structural integrity of the skin, including collagen and elastin pathways, which are known to be affected by both intrinsic aging and environmental stressors. Research has employed computational approaches such as molecular docking and molecular dynamics simulations to investigate how Vialox may interact with relevant biological targets at a structural level. In vitro methodologies have also been incorporated into this research to complement the in silico findings, providing a more integrative picture of the peptide's potential bioactivity. This type of combined computational and laboratory-based investigation represents a growing area of interest in cosmeceutical peptide research, where scientists seek to better understand the mechanisms through which small peptides may influence cellular and molecular processes in skin tissue models.